Eupatilin attenuates TGF-β2-induced proliferation and epithelial-mesenchymal transition of retinal pigment epithelial cells.

作者: Suat Erdogan , Riza Serttas , S Altan Ozal , Ayca Kupeli Cinar

DOI: 10.1080/15569527.2021.1902343

关键词: PigmentTransition (genetics)Cell biologyProliferative vitreoretinopathyEupatilinRetinalTransforming growth factorAdhesionChemistryEpithelial–mesenchymal transition

摘要: The main characteristic of proliferative vitreoretinopathy (PVR) is migration, adhesion, and epithelial-mesenchymal transition (EMT) retinal pigment epithelial cells (RPE). Eupatilin a natura...

参考文章(43)
Oh Woong Kwon, Ji Hun Song, Mi In Roh, Retinal Detachment and Proliferative Vitreoretinopathy. Developments in ophthalmology. ,vol. 55, pp. 154- 162 ,(2016) , 10.1159/000438972
D. M. Gonzalez, D. Medici, Signaling mechanisms of the epithelial-mesenchymal transition Science Signaling. ,vol. 7, ,(2014) , 10.1126/SCISIGNAL.2005189
Samy Lamouille, Jian Xu, Rik Derynck, Molecular mechanisms of epithelial–mesenchymal transition Nature Reviews Molecular Cell Biology. ,vol. 15, pp. 178- 196 ,(2014) , 10.1038/NRM3758
Shigeo Tamiya, LanHsin Liu, Henry J Kaplan, None, Epithelial-mesenchymal transition and proliferation of retinal pigment epithelial cells initiated upon loss of cell-cell contact. Investigative Ophthalmology & Visual Science. ,vol. 51, pp. 2755- 2763 ,(2010) , 10.1167/IOVS.09-4725
I KIM, J ARROYO, Mechanisms in proliferative vitreoretinopathy. Ophthalmology Clinics of North America. ,vol. 15, pp. 81- 86 ,(2002) , 10.1016/S0896-1549(01)00008-6
Cosetta Bertoli, Jan M. Skotheim, Robertus A. M. de Bruin, Control of cell cycle transcription during G1 and S phases Nature Reviews Molecular Cell Biology. ,vol. 14, pp. 518- 528 ,(2013) , 10.1038/NRM3629
Eun-Ju Choi, Soyoung Lee, Jeong-Ryong Chae, Hyun-Shik Lee, Chang-Duk Jun, Sang-Hyun Kim, Eupatilin inhibits lipopolysaccharide-induced expression of inflammatory mediators in macrophages Life Sciences. ,vol. 88, pp. 1121- 1126 ,(2011) , 10.1016/J.LFS.2011.04.011
Ch. Baudouin, P. Hofman, F. Brignole, J. Bayle, R. Loubière, P. Gastaud, Immunocytology of cellular components in vitreous and subretinal fluid from patients with proliferative vitreoretinopathy. Ophthalmologica. ,vol. 203, pp. 38- 46 ,(1991) , 10.1159/000310223
Hamid Ahmadieh, Mostafa Feghhi, Homa Tabatabaei, Nasser Shoeibi, Alireza Ramezani, Mohammad Reza Mohebbi, Triamcinolone acetonide in silicone-filled eyes as adjunctive treatment for proliferative vitreoretinopathy: a randomized clinical trial. Ophthalmology. ,vol. 115, pp. 1938- 1943 ,(2008) , 10.1016/J.OPHTHA.2008.05.016
Jung-Hoon Cho, Jong-Gyu Lee, Yeong-In Yang, Ji-Hyun Kim, Ji-Hye Ahn, Nam-In Baek, Kyung-Tae Lee, Jung-Hye Choi, Eupatilin, a dietary flavonoid, induces G2/M cell cycle arrest in human endometrial cancer cells Food and Chemical Toxicology. ,vol. 49, pp. 1737- 1744 ,(2011) , 10.1016/J.FCT.2011.04.019