Recycling and refurbishing old antitubercular drugs: the encouraging case of inhibitors of mycolic acid biosynthesis

作者: Juan M Belardinelli , Héctor R Morbidoni

DOI: 10.1586/ERI.13.24

关键词: Molecular targetsMycobacterium tuberculosisDrug developmentBiochemistryMycolic acid biosynthesisBiologyMechanism of actionPharmacology

摘要: One of the first approaches undertaken in the quest for antitubercular compounds was that of understanding the mechanism of action of old drugs and proposing chemical modifications …

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