Analytical biochemistry system with robotically carried bioarray

作者: Jack D. McNeal , David E. Helphrey , Peter J. Coassin

DOI:

关键词: Sample (material)Adapter (genetics)BiomoleculeMicrotiter plateAnalytical chemistryChemistryPipetteLight scatteringSubstrate (printing)Robotic arm

摘要: An analytical biochemistry system featuring a substrate with reactants immobilized thereon at fixed, known locations, holder supporting the and manipulator for transporting to fixed sample an inspection station. The are binding agents target biomolecule in which forms bound substance having detectable characteristic. may be standard pipettor, optionally carried by robot arm or hand as contact detection of presence biomolecules within sample. In one embodiment, is pipette tip housed, it adapter bears fits wells microtiter plate. After appropriate incubation, moved from sample, exposed any necessary development steps before being location probing, such beam. Probing performed identify complexing on substrate, accomplished via fluorescence detection, light scattering, autoradiography, some other method.

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