Seasonal Variation of Fibrinogen in Dipper and Nondipper Hypertensive Patients

摘要: Background— A seasonal variation with higher values in winter has been previously reported plasma fibrinogen, a recognized marker of the potential risk myocardial infarction and stroke. The lack nocturnal decline blood pressure also associated an increase cardiovascular events. Accordingly, we have compared yearly fibrinogen dipper nondipper hypertensive patients. Methods Results— We studied 1006 stage 1 to 2 patients (482 men 524 women, 53.0±13.4 years age). Blood was measured every 20 minutes during day 30 at night for 48 consecutive hours. Physical activity simultaneously evaluated 1-minute intervals wrist actigraph. sample collected on same before starting monitoring. circannual established all as well subgroups dippers nondippers (n=513; <10%) by mu...