Methods of treating neuroendocrine tumors using frizzled-binding agents
作者： Robert Joseph Stagg , Jakob Dupont
DOI:
关键词: Effective dose (pharmacology) 、 Neuroendocrine tumors 、 Wnt antagonists 、 Antibody 、 Medicine 、 Receptor 、 Frizzled 、 Pharmacology
摘要: Novel methods of treating neuroendocrine tumors are provided. In one embodiment, the method comprises administering to a subject in need thereof therapeutically effective dose Wnt antagonist. antagonist is an anti-FZD antibody. another soluble FZD receptor polypeptide. further anti-Wnt
lens.org参考文章(390)
Albert Lai, Guoying K. Yu, Methods of treating, diagnosing or detecting cancer ,(2007)
Chien-Hsing Ken Chang, Edmund Rossi, David Goldenberg, Methods of generating multispecific, multivalent agents from vh and vl domains ,(2002)
Sanjeev H. Satyal, Fumiko Takada Axelrod, Timothy Charles Hoey, Satyajit Sujit Kumar Mitra, Aaron Ken Sato, Austin L. Gurney, Methods of use for an antibody against human frizzled receptors 1, 2. 5, 7 or 8 ,(2011)
Matthew Weitzman, Krishna J. Fisher, James M. Wilson, Shu-Jen Chen, Adenovirus and methods of use thereof ,(1995)
Jean-Francois Dedieu, Martine Latta, Patrice Yeh, Emmanuelle Vigne, Michel Perricaudet, Targeted adenovirus vectors for delivery of heterologous genes ,(1999)
Seiji Sakano, Akira Itoh, Differentiation-suppressive polypeptide ,(1996)
John J. Kopchick, Wen Y. Chen, Methods for treating acromegaly and giantism with growth hormone antagonists ,(1995)
Richard Grant Fehon, Ilaria Rebay, Spyridon Artavanis-Tsakonas, Serrate fragments and derivatives ,(1994)
Masahiro Tsutsumi, Masanobu Oshima, Makoto M. Taketo, Masahiko Kobayashi, Hiroko Oshima, Morphological and Molecular Processes of Polyp Formation in ApcΔ716 Knockout Mice Cancer Research. ,vol. 57, pp. 1644- 1649 ,(1997)
David L. Rimm, Stephen C. Wardlaw, Paul Fiedler, Robert A. Levine, Method for the detection, identification, enumeration and confirmation of circulating cancer cells and/or hemotologic progenitor cells in whole blood ,(1997)