Recent Advances in the Molecular Mechanisms Underlying Pyroptosis in Sepsis.

作者: Yu-Lei Gao , Jian-Hua Zhai , Yan-Fen Chai

DOI: 10.1155/2018/5823823

关键词: ImmunologyMultiple organ dysfunction syndromeSepsisInnate immune systemPyroptosisProinflammatory cytokineSecondary infectionSeptic shockLipopolysaccharideMedicine

摘要: … Even so, pyroptosis when overactivated can result in septic shock, … of pyroptosis in activated innate immune cells and endothelial cells stimulated by cytosolic lipopolysaccharide (LPS). …

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