作者: Wilfried Weber , Hanna J. Wagner , Hasti Mohsenin
DOI: 10.1007/10_2020_158
关键词: Analytics 、 Biochemical engineering 、 Toolbox 、 Synthetic biology 、 Biomedicine 、 Network topology 、 Medical diagnostic 、 Self-healing hydrogels 、 Heavy metals
摘要: Synthetic biology is strongly inspired by concepts of engineering science and aims at the design generation artificial biological systems in different fields research such as diagnostics, analytics, biomedicine, or chemistry. To this aim, synthetic uses an approach relying on a toolbox molecular sensors switches that endows cellular hosts with non-natural computing functions circuits. Importantly, concept not only limited to approaches. building blocks have also conferred sensing switching capability otherwise inactive materials. This principle has attracted high interest for development biohybrid materials capable responding specific stimuli, disease biomarkers, antibiotics, heavy metals. Moreover, interconnection individual sense-and-respond complex enabled processing of, example, multiple inputs amplification signals using feedback topologies. Such holding potential applications analytical diagnostic sectors will be described chapter.