Lipids in Mammalian Hibernation and Artificial Hypobiosis

摘要: Membrane lipids-phospholipids, fatty acids, and cholesterol-participate in thermal adaptation of ectotherms (bacteria, amphibians, reptiles, fishes) mainly via changes membrane viscosity caused by the degree acids unsaturation, cholesterol/phospholipids ratio, phospholipid composition. Studies endotherms (mammals birds) revealed regulatory role lipids hibernation. Cholesterol participate regulation parameters torpor, gene expression, activity enzymes lipid metabolism. Some metabolism during artificial natural hypobiosis, namely, increased concentration cholesterol blood decreased neocortex, are analogous to those observed under stress conditions coincide with mammalian nonspecific reactions environmental agents. It is shown that effects hypobiosis on composition cell membranes different. Changes cause morphology The effect organelles specific seems be defined signaling systems. Comparative study promising for elucidation mammals low ambient temperatures.