Awake apnea associated with gastroesophageal reflux: A specific clinical syndrome

作者: Alan R. Spitzer , John T. Boyle , David N. Tuchman , William W. Fox

DOI: 10.1016/S0022-3476(84)80992-0

关键词: RefractoryAnesthesiaMedicineHeart rateRefluxApneaNissen fundoplicationEsophagitisAirway obstructionClinical syndromePediatrics, Perinatology, and Child Health

摘要: Fifteen infants with a specific clinical history including awake apnea were evaluated and compared control group of infants, using 24-hour studies esophageal pH, nasal thermistor, impedance pneumography, heart rate. Thirteen the 15 children had clearly documented episodes airway obstruction in associated gastroesophageal reflux occurring at least twice during study (mean 3.9±0.7, range 2 to 9). The did not show similar findings. All frequent reflux. Treatment home monitoring precautions was successful 10 15. Five received therapy urecholine hydrochloride because continuing reflux-associated apnea. Two subsequently required Nissen fundoplication, primarily for symptoms severe esophagitis. Our data suggest that apnea, is Medical management usually successful, but fundoplication may be needed refractory cases.

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