Recurrent laryngeal nerve paralysis after thyroid cancer surgery and intraoperative nerve monitoring.

作者: Kayoko Mizuno , Masato Takeuchi , Yuji Kanazawa , Morimasa Kitamura , Kazuki Ide

DOI: 10.1002/LARY.27698

关键词: Logistic regressionThyroid cancerRecurrent laryngeal nerveConfidence intervalOdds ratioMedicineParalysisSurgeryRetrospective cohort studyIncidence (epidemiology)

摘要: Objectives/hypothesis This study aimed to investigate the risk of postoperative recurrent laryngeal nerve paralysis (RLNP) with and without use intraoperative monitoring (IONM) during thyroid cancer surgery. Study design Retrospective cohort study. Methods utilized a nationwide claims database in Japan. Patients who underwent surgery IONM were included, RLNP incidence was compared. Results The included 5,804 patients. Multivariable logistic regression analysis revealed that not associated increased (odds ratio: 1.15; 95% confidence interval: 0.67-1.96). There no significant effect on prevention when stratified by tumor or nodal classification. Rather, patients had T4 N1b classifications received higher incidences RLNP. Conclusions Use did significantly reduce results for populations may be explained indication bias unmeasured confounders. Level evidence NA Laryngoscope, 129:1954-1960, 2019.

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