Phospholipases in human parturition.

作者: T Wilson

DOI: 10.1071/RD9900511

关键词: Protein kinase CEndocrinologyCell biologyAnnexinPhospholipasePhospholipase A2StimulationCell membraneEnzymeBiologyReproductive technologyInternal medicine

摘要: Phospholipase A2 plays a major role in controlling PG synthesis. Regulation of the activity this enzyme probably holds key to onset labour. Both PLA2 and PLC can contribute arachidonate release production cells, but appears be main activated independently each other; an influx external calcium is required for activation. It suggested that contributes synthesis through product stimulation protein kinase C which maintains pool free by inhibiting reincorporation into cell membrane. The regulatory lipocortin phospholipase inhibition controversial unlikely relevant

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