Genetic variants associated with phenytoin-related severe cutaneous adverse reactions.

作者: Wen-Hung Chung , Wan-Chun Chang , Yun-Shien Lee , Ying-Ying Wu , Chih-Hsun Yang

DOI: 10.1001/JAMA.2014.7859

关键词: DermatologyCase-control studyPopulationToxic epidermal necrolysisMedicinePathologyEosinophiliaAdverse effectGenome-wide association studyOdds ratioPharmacogenetics

摘要: Importance The antiepileptic drug phenytoin can cause cutaneous adverse reactions, ranging from maculopapular exanthema to severe cutaneous adverse reactions, which include …

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