Effect of Red Blood Cell Transfusion on Unfavorable Neurologic Outcome and Symptomatic Vasospasm in Patients with Cerebral Aneurysmal Rupture: Old versus Fresh Blood.
作者： Eugene Kim , Hyun-Chang Kim , Sang-Youn Park , Young-Jin Lim , Soo-Han Ro
DOI: 10.1016/J.WNEU.2015.08.024
关键词: Medicine 、 Subarachnoid hemorrhage 、 Anesthesia 、 Modified Rankin Scale 、 Surgery 、 Cerebral vasospasm 、 C-reactive protein 、 Cerebral infarction 、 Red blood cell 、 Interquartile range 、 Blood transfusion
摘要: Background Red blood cell (RBC) transfusion, especially with "old" blood, is associated adverse clinical outcomes. We compared the effects of fresh versus old transfusion on poor neurologic outcomes and symptomatic vasospasm in patients ruptured cerebral aneurysms. Methods In this retrospective study, 211 aneurysmal rupture were divided into 3 groups: nontransfusion ( n = 136), (RBC storage ≤14 days) 39), >14 36). Unfavorable (modified Rankin Scale score ≥3) assessed. Results The incidence unfavorable was significantly higher groups nontransfused group (71.8% 58.3% vs. 21.3%; P Conclusions RBC itself, regardless duration storage, Also, but not increased vasospasm.
dissem.in参考文章(42)
Daniel B. Kim-Shapiro, Janet Lee, Mark T. Gladwin, Storage lesion: role of red blood cell breakdown. Transfusion. ,vol. 51, pp. 844- 851 ,(2011) , 10.1111/J.1537-2995.2011.03100.X
Tomikatsu Toyoda, Ichiro Yonekura, Akira Iijima, Munehisa Shinozaki, Takeo Tanishima, Clot-clearance rate in the sylvian cistern is associated with the severity of cerebral vasospasm after subarachnoid hemorrhage. Acta Neurochirurgica. ,vol. 120, pp. 275- 277 ,(2015) , 10.1007/978-3-319-04981-6_46
Ryszard M. Pluta, Dysfunction of nitric oxide synthases as a cause and therapeutic target in delayed cerebral vasospasm after SAH. Acta Neurochirurgica. ,vol. 104, pp. 139- 147 ,(2008) , 10.1007/978-3-211-75718-5_28
Eldad A. Hod, Ning Zhang, Set A. Sokol, Boguslaw S. Wojczyk, Richard O. Francis, Daniel Ansaldi, Kevin P. Francis, Phyllis Della-Latta, Susan Whittier, Sujit Sheth, Jeanne E. Hendrickson, James C. Zimring, Gary M. Brittenham, Steven L. Spitalnik, Transfusion of red blood cells after prolonged storage produces harmful effects that are mediated by iron and inflammation Blood. ,vol. 115, pp. 4284- 4292 ,(2010) , 10.1182/BLOOD-2009-10-245001
Gregor Broessner, Peter Lackner, Clemens Hoefer, Ronny Beer, Raimund Helbok, Christoph Grabmer, Hanno Ulmer, Bettina Pfausler, Christian Brenneis, Erich Schmutzhard, Influence of red blood cell transfusion on mortality and long-term functional outcome in 292 patients with spontaneous subarachnoid hemorrhage. Critical Care Medicine. ,vol. 37, pp. 1886- 1892 ,(2009) , 10.1097/CCM.0B013E31819FFD7F
Lauralyn A McIntyre, Dean A Fergusson, James S Hutchison, Giuseppe Pagliarello, John C Marshall, Elizabeth Yetisir, Gregory MT Hare, Paul C Hébert, Canadian Critical Care Trials Group, Effect of a liberal versus restrictive transfusion strategy on mortality in patients with moderate to severe head injury. Neurocritical Care. ,vol. 5, pp. 4- 9 ,(2006) , 10.1385/NCC:5:1:4
Peter D. Le Roux, J. Paul Elliott, H. Richard Winn, Blood Transfusion during Aneurysm Surgery Neurosurgery. ,vol. 49, pp. 1068- 1075 ,(2001) , 10.1097/00006123-200111000-00009
Santiago R Leal-Noval, Manuel Múñoz-Gómez, Francisco Murillo-Cabezas, None, Optimal hemoglobin concentration in patients with subarachnoid hemorrhage, acute ischemic stroke and traumatic brain injury. Current Opinion in Critical Care. ,vol. 14, pp. 156- 162 ,(2008) , 10.1097/MCC.0B013E3282F57577
Robert D Stevens, Neeraj S Naval, Marek A Mirski, Giuseppe Citerio, Peter J Andrews, None, Intensive care of aneurysmal subarachnoid hemorrhage: An international survey Intensive Care Medicine. ,vol. 35, pp. 1556- 1566 ,(2009) , 10.1007/S00134-009-1533-1
Andrew M. Naidech, Borko Jovanovic, Katja E. Wartenberg, Augusto Parra, Noeleen Ostapkovich, E Sander Connolly, Stephan A. Mayer, Christopher Commichau, Higher hemoglobin is associated with improved outcome after subarachnoid hemorrhage* Critical Care Medicine. ,vol. 35, pp. 2383- 2389 ,(2007) , 10.1097/01.CCM.0000284516.17580.2C