Three-year outcome after balloon aortic valvuloplasty. Insights into prognosis of valvular aortic stenosis

摘要: BACKGROUND To identify predictors of long-term outcome after balloon aortic valvuloplasty, we analyzed data on 674 adults (mean age, 78 +/- 9 years; 56% were women) undergoing this procedure at 24 clinical centers who had a mean initial increase in valve area 0.3 cm2. METHODS AND RESULTS Baseline included clinical, echocardiographic, and catheterization variables. Follow-up mortality, cause death, rehospitalization, 6-month echocardiography, functional status. Kaplan-Meier curves log-rank tests used to evaluate survival subgroups. Multivariate Cox regression models independent survival. Overall was 55% 1 year, 35% 2 years, 23% 3 with the majority deaths (70%) classified as cardiac by an review committee. Rehospitalization common (64%), although 61% survivors years reported improved symptoms. Echocardiography 6 months (n = 115) showed restenosis from postprocedural 0.78 0.31 cm2 0.65 0.25 (P CONCLUSIONS Long-term valvuloplasty is poor 1- 3-year rates 23%, respectively. Although report fewer symptoms, early recurrent hospitalization are common.