Small tumour size is associated with new-onset chronic kidney disease after radical nephrectomy in patients with renal cell carcinoma

摘要: Abstract Background To investigate the impact of tumour size on postoperative glomerular filtration rate (GFR) in patients undergoing radical nephrectomy (RN) for renal cell carcinoma (RCC). Methods We retrospectively identified 1371 who underwent RN between 1995 and 2010. Serum creatinine levels were measured preoperatively, within 7days RN, at 3months, 1 3years. divided into three groups based size: A: ⩽4cm, B: 4–7cm, C: >7cm. The changes GFR compared multivariate logistic regression was used to analyse predictive value new-onset chronic kidney disease (CKD, 2 ). Results preoperative significantly different among (A: 83.0, 82.0, 79.4ml/min/1.73m , P =0.040). decrease from greater group A than B C (28.2 versus 24.2 18.5ml/min/1.73m =0.009), contrast GFR. incidence >30% higher Group Groups 1year (52.4% 41.5% 33.7%, Conclusions Small is associated with CKD after RN. Partial should be considered 7cm or less.