Metabolism of gammexane in flies, ticks and locusts.

摘要: THE insecticide gammexane is known to be converted into water-soluble compounds in a variety of invertebrates1, but the nature these metabolites not known. Some indication their structure has been given by Bradbury and Standen2, who obtained mixture dichlorothiophenols after alkaline hydrolysis excreta from poisoned flies. It also that homogenates flies require glutathione if enzymatic conversion derivatives occur2. These results have suggested compound like S-(pentachlorocyclohexyl)glutathione might metabolite, this hypothesis supported presence highly active enzymes insects which catalyse condensation other chloro-compounds with glutathione3.