P300 latency reflects the degree of cognitive decline in dementing illness
作者： John Polich , Cindy L. Ehlers , Shirley Otis , Arnold J. Mandell , Floyd E. Bloom
DOI: 10.1016/0013-4694(86)90007-6
关键词: Psychiatry 、 Alzheimer's disease 、 Dementia 、 Cerebral infarction 、 Cognitive decline 、 Audiology 、 Latency (engineering) 、 Psychology 、 Degree (music) 、 Cognition 、 Electroencephalography
摘要: Abstract An auditory discrimination paradigm was employed to elicit the P3 component of event-related brain potential (ERP) from 39 demented patients (mean age = 71 years). Component latency longer in who were diagnosed as having primary degenerative dementia and other cognitive impairment disorders compared age-matched controls. Neurologist ratings significantly correlated with values, although no differences mean obtained between various categories dementia. ERP measurement techniques interpretation an index dementing illness are discussed.
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