Preconception Blood Pressure and Risk of Low Birth Weight and Small for Gestational Age: A Large Cohort Study in China.

摘要: Our objective was to examine whether high blood pressure in the preconception period associated with low birth weight (LBW) and small-for-gestational age (SGA) Chinese women. Data were obtained from China-US Collaborative Project for Neural Tube Defects Prevention, a large population-based cohort study. We included 43 718 singleton live births delivered at gestational ages of 28-45 weeks women who registered before pregnancy 7 counties southern China. Blood measured during registration by trained healthcare workers, other health-related information recorded prospectively. used logistic regression evaluate associations between risk LBW SGA, adjusting potential confounders. The prevalence hypertension study population 4.62% (2019/43 718). incidences SGA 2.33% 5.05% group 2.01% 5.68% nonhypertension group. Compared group, did not show significantly increased overall (adjusted ratio =1.16, 95% confidence interval 0.86-1.57) or =0.89, 0.73-1.09). When participants normal as reference, adjusted prehypertensive 1.13 (95% 1.03-1.25). results do support an association higher SGA.