Nitrogen-terminated silicon nanoparticles obtained via chemical etching and passivation are specific fluorescent probes for creatinine.

摘要: A method is described here to prepare water-dispersible nitrogen-functionalized silicon nanoparticles (N-SiNPs). It consists of two steps, viz. etching the oxidized shell SiNPs and nitrogen-passivation exposed silicon. The resulting N-SiNPs have an average diameter 2.6±0.7 nm show blue fluorescence (with excitation/emission peaks at 340/420 nm). quantum yield 23% decay time in nanosecond regime. Compared methods using a plasma or hydrofluoric acid, process (etching passivation) mild, continuous, fast, air-compatible. modified with chlorotetracycline are shown be viable fluorescent probe for creatinine. Fluorescence drops 0 20 μM creatinine concentration range, limit detection 0.14 μM.