Production of full-length soluble Plasmodium falciparum RH5 protein vaccine using a Drosophila melanogaster Schneider 2 stable cell line system.

作者: Kathryn A Hjerrild , Jing Jin , Katherine E Wright , Rebecca E Brown , Jennifer M Marshall

DOI: 10.1038/SREP30357

关键词: VirologyAntigenImmunogenBiologyDrosophila melanogasterBasiginSchneider 2 cellsMonoclonal antibodyAntibodyPlasmodium falciparum

摘要: The Plasmodium falciparum reticulocyte-binding protein homolog 5 (PfRH5) has recently emerged as a leading candidate antigen against the blood-stage human malaria parasite. …

参考文章(60)
Peter G. Kremsner, Ayôla Akim Adegnika, Saadou Issifou, Bertrand Lell, Selidji Todagbe Agnandji, Emmanuel B. Bache, Benjamin Gottlieb Mordmüller, José Francisco Fernandes, Abraham Sunday Alabi, Béatrice Peggy Abossolo, Marguerite M. Loembe, Anita Lumeka Kabwende, Efficacy and safety of RTS,S/AS01 malaria vaccine with or without a booster dose in infants and children in Africa: final results of a phase 3, individually randomised, controlled trial. The Lancet. ,vol. 386, pp. 31- 45 ,(2015) , 10.15496/PUBLIKATION-6508
Simon J. Draper, Evelina Angov, Toshihiro Horii, Louis H. Miller, Prakash Srinivasan, Michael Theisen, Sumi Biswas, Recent advances in recombinant protein-based malaria vaccines. Vaccine. ,vol. 33, pp. 7433- 7443 ,(2015) , 10.1016/J.VACCINE.2015.09.093
Thomas M. Daly, Paul A. Calvo, Carole A. Long, Yang Kang, Comparison of Humoral Immune Responses Elicited by DNA and Protein Vaccines Based on Merozoite Surface Protein-1 from Plasmodium yoelii, a Rodent Malaria Parasite Journal of Immunology. ,vol. 161, pp. 4211- 4219 ,(1998)
Marilis Rodriguez, Sara Lustigman, Estrella Montero, Yelena Oksov, Cheryl A. Lobo, PfRH5: A Novel Reticulocyte-Binding Family Homolog of Plasmodium falciparum that Binds to the Erythrocyte, and an Investigation of Its Receptor PLoS ONE. ,vol. 3, pp. e3300- ,(2008) , 10.1371/JOURNAL.PONE.0003300
Susanne H Sheehy, Christopher JA Duncan, Sean C Elias, Katharine A Collins, Katie J Ewer, Alexandra J Spencer, Andrew R Williams, Fenella D Halstead, Samuel E Moretz, Kazutoyo Miura, Christian Epp, Matthew DJ Dicks, Ian D Poulton, Alison M Lawrie, Eleanor Berrie, Sarah Moyle, Carole A Long, Stefano Colloca, Riccardo Cortese, Sarah C Gilbert, Alfredo Nicosia, Adrian VS Hill, Simon J Draper, Phase Ia Clinical Evaluation of the Plasmodium Falciparum Blood-Stage Antigen MSP1 in ChAd63 and MVA Vaccine Vectors Molecular Therapy. ,vol. 19, pp. 2269- 2276 ,(2011) , 10.1038/MT.2011.176
Sowmya Sampath, Chris Carrico, Joel Janes, Sairam Gurumoorthy, Claire Gibson, Martin Melcher, Chetan E. Chitnis, Ruobing Wang, William R. Schief, Joseph D. Smith, Glycan Masking of Plasmodium vivax Duffy Binding Protein for Probing Protein Binding Function and Vaccine Development PLOS Pathogens. ,vol. 9, ,(2013) , 10.1371/JOURNAL.PPAT.1003420
Kazuhiro Aoki, Mindy Perlman, Jae-Min Lim, Rebecca Cantu, Lance Wells, Michael Tiemeyer, Dynamic developmental elaboration of N-linked glycan complexity in the Drosophila melanogaster embryo Journal of Biological Chemistry. ,vol. 282, pp. 9127- 9142 ,(2007) , 10.1074/JBC.M606711200
Damien R. Drew, James G. Beeson, PfRH5 as a candidate vaccine for Plasmodium falciparum malaria. Trends in Parasitology. ,vol. 31, pp. 87- 88 ,(2015) , 10.1016/J.PT.2015.02.001
David E. Clements, Beth-Ann G. Coller, Michael M. Lieberman, Steven Ogata, Gordon Wang, Kent E. Harada, J. Robert Putnak, John M. Ivy, Michael McDonell, Gary S. Bignami, Iain D. Peters, Julia Leung, Carolyn Weeks-Levy, Eileen T. Nakano, Tom Humphreys, Development of a recombinant tetravalent dengue virus vaccine: Immunogenicity and efficacy studies in mice and monkeys Vaccine. ,vol. 28, pp. 2705- 2715 ,(2010) , 10.1016/J.VACCINE.2010.01.022