Cyclic adenosine monophosphate (cAMP) production in avian theca cells during follicular maturation

摘要: LH was used to stimulate cAMP production in theca cells from the 5 largest preovulatory follicles of hens and this related LH-stimulated androstenedione same cells. stimulated by extent each follicle. However, not effective stimulating follicle (T1), although greatly increased smaller (T2-T5). Effects similar those on were observed response forskolin, indicating that intrinsic adenylate cyclase activity In addition, forskolin unable T1 Our results provide evidence levels receptor-mediated non-receptor-mediated are follicles. We conclude step restricts ability produce androgen is distal generation.