The effects of soy milk and isoflavone supplements on cognitive performance in healthy, postmenopausal women

摘要: Rationale: The decline in estrogen concentrations women after menopause can contribute to health- related changes including impairments cognition, especially memory. Because of the health concerns hormone replacement therapy (HRT), alternative approaches treat menopausal symptoms, such as nutritional supplements and/or diet containing isoflavones, are interest. Objectives: This study investigated whether soy isoflavones (soy milk and supplement) could improve cognitive functioning healthy, postmenopausal women. Participants, Intervention Design: A total 79 women, 48-65 years age, completed a double-blind, placebo-controlled trial which they were randomly assigned one three experimental groups: cow's placebo supplement (control); milk, 72 mg isoflavones/day); or isoflavone (isoflavone supplement, 70 isoflavones/day). Measurements: Cognitive was assessed using various tasks before intervention (baseline) (test). Results: In contrast predictions, did not selective attention (Stroop task), visual long-term memory (pattern recognition), short-term visuo- spatial (Benton Visual Retention Test), visuo-spatial working (color match task). Also, group showed verbal (Digit Ordering Task) compared control groups. Conclusion: Soy consumed food over 16-week period appreciably affect