The role of TP53 in acute myeloid leukemia: Challenges and opportunities.
作者： Karina Barbosa , Sha Li , Peter D. Adams , Aniruddha J. Deshpande
DOI: 10.1002/GCC.22796
关键词: DNA repair 、 Tumor suppressor gene 、 Cancer 、 Senescence 、 Leukemia 、 Mutant 、 Biology 、 Cancer research 、 Gene 、 Myeloid leukemia
摘要: … non-TP53 mutated AML, and (c) targeting mutant TP53 in TP53 mutant AML or leveraging wild-type TP53 status in unmutated AMLs is an important consideration for designing anti-AML …
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