Multivariate Analysis of Risk Factors for Coronary Heart Disease

作者: Lars Wilhelmsen

DOI: 10.1161/01.CIR.48.5.950

关键词: Prospective cohort studyHematocritMedicinePopulationMultivariate analysisMyocardial infarctionCholesterolInternal medicineSurgeryBlood pressureLogistic regression

摘要: For a prospective study of risk factors for coronary heart disease (CHD), defined as acute nonfatal myocardial infarction and fatal CHD, 973 men, all aged 50 years, were recruited from general Swedish urban population. Of the 855 who agreed to participate, 834 showed no signs CHD selected observed nine years four months. Autopsies performed on except two 55 patients died during study. Forty-four men developed clinical manifestations this time; 19 them died. Using multiple logistic model, we analyzed probable factors. The presence high serum cholesterol, smoking, systolic blood pressure, dyspnea, registration by Temperance Board increased events related significantly. triglycerides, hematocrit readings, geographic mobility did not cause significant increase in CHD. Those with sedentary jobs slightly tende...

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