Global features of sequences of bacterial chromosomes, plasmids and phages revealed by analysis of oligonucleotide usage patterns.

作者: Oleg N Reva , Burkhard Tümmler

DOI: 10.1186/1471-2105-5-90

关键词: BiologyGeneticsOligonucleotideDNA microarrayDna viralBacterial genome sizeGenetic variationPlasmidCircular bacterial chromosome

摘要: Background Oligonucleotide frequencies were shown to be conserved signatures for bacterial genomes, however, the underlying constraints have yet not been resolved in detail. In this paper we analyzed oligonucleotide usage (OU) biases a comprehensive collection of 155 completely sequenced chromosomes, 316 plasmids and 104 phages.

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