Highly active antiretroviral therapy and viral response in HIV type 2 infection.
作者： C. Mullins , G. Eisen , S. Popper , A. D. Sarr , J.-L. Sankale
DOI: 10.1086/421390
关键词: Virus 、 Internal medicine 、 Viral load 、 Immunopathology 、 Medicine 、 Lentivirus 、 Viral disease 、 Clinical trial 、 Sida 、 Immunology 、 Acquired immunodeficiency syndrome (AIDS)
摘要: Human immunodeficiency virus type 2 (HIV-2), the second human retrovirus known to cause AIDS, is endemic West Africa but infrequently found outside this region. We present a case series of 10 HIV-2--infected individuals treated in United States. Physicians applied principles highly active antiretroviral therapy (HAART), normally used treating HIV 1, with modifications considered appropriate for HIV-2. CD4+ cell count, HIV-2 load, and clinical status were correlate well, providing evidence that load useful managing treatment patients who are receiving therapy. However, HAART regimens predicted efficacy 1 infection not as efficacious Controlled trials HIV-2-infected various needed provide therapeutic guidance medical community.
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