作者: Sylvia Martin-Stone
DOI: 10.1007/978-3-642-40418-4_6
关键词: Tranexamic acid 、 Medication history 、 Heparin 、 Anticoagulant 、 Perioperative 、 Medicine 、 Coagulopathy 、 Cardiac surgery 、 Thrombotic thrombocytopenic purpura 、 Intensive care medicine
摘要: Maintaining the delicate balance of thrombostasis postoperatively requires attention to preoperative, intraoperative, and postoperative effects on coagulation cascade. Identifying preoperative risk factors for bleeding including medication history, comorbid conditions, prior complications is an integral part preventing complications. Outpatient anticoagulant therapies are rapidly evolving with development novel medications targeting specific such as thrombin factor Xa. These agents require understanding their limitations in perioperative period. Additionally, interplay between cascade external affecting platelet quantity function can help direct management Applying appropriate monitoring techniques result interpretation guide therapy especially coagulopathic disease states disseminated intravascular coagulopathy (DIC) thrombocytopenia due a variety specifically heparin.