EZH2 and KDM6A Act as an Epigenetic Switch to Regulate Mesenchymal Stem Cell Lineage Specification

作者: Sandra Isenmann , Lachlan Cooper , Danijela Menicanin , Andrew Zannettino , Stan Gronthos

DOI: 10.1002/STEM.1573

关键词: Cancer researchMesenchymal stem cellDemethylaseStem cellBiologyGene knockdownChromatinEpigeneticsAdipogenesisEZH2

摘要: … the DNA methylation profile of both adipogenic and nonadipogenic genes in MSC-like cells derived from human adipose tissue found that the promoters for four adipogenic genes (…

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