Synthesis of hierarchical macro/mesoporous dicalcium phosphate monolith via epoxide-mediated sol–gel reaction from ionic precursors

摘要: Starting from calcium chloride dihydrate (CaCl2·2H2O), phosphoric acid (H3PO4), and poly(acrylic acid) (PAA) dissolved in a mixture of water methanol (MeOH), dicalcium phosphate anhydrous (DCPA, CaHPO4) monoliths with co-continuous macropores mesopores have been synthesized by the addition propylene oxide. Macropores are formed as result phase separation, while interstices between primary particles size ca. 30 nm. Propylene oxide acts proton scavenger leads to moderate pH increase reaction solution, which brings about gelation several minutes. On other hand, PAA crystal growth inhibitor well separation inducer. The extensive DCPA is hindered allows morphological control structure micrometer range. Fourier transform infrared spectroscopy indicates that form composite via interaction carboxyl groups surface crystals, together gel phase. solvent phase, converted after evaporative drying, mainly comprised solvent. degree supersaturation solution considerably influence on crystallization process, thereby, influences porous nano- ranges.