The Risk of Infection after Nasal Colonization with Staphylococcus Aureus

摘要: Abstract Purpose Nasal, axillary, or inguinal colonization with Staphylococcus aureus generally precedes invasive infection. Some studies have found that methicillin-resistant S. (MRSA) poses a greater risk of clinical infection than methicillin-susceptible (MSSA). However, the magnitude is unclear. Methods We undertook systematic review to provide an overall estimate following MRSA compared by MSSA. Ten observational studies, total 1170 patients, were identified provided data on both MSSA and A random-effects model was used obtain pooled estimates odds ratio 95% confidence interval. Results Overall, associated 4-fold increase in (odds 4.08, interval, 2.10-7.44). Studies differed choice patient population, severity illness, frequency sampling detect colonization. Conclusion Further research needed identify effective methods for sustained eradication carriage reduce high subsequent