Mitochondrial permeability transition and its regulatory components are implicated in apoptosis of primary cultures of rat proximal tubular cells exposed to lead.

作者: Gang Liu , Zhong-Kun Wang , Zhen-Yong Wang , Du-Bao Yang , Zong-Ping Liu

DOI: 10.1007/S00204-015-1547-0

关键词: Mitochondrial permeability transition poreMPTPANTApoptosisVoltage-dependent anion channelBiologyCell biologyBiochemistryCell cultureMitochondrionCytochrome c

摘要: … mitochondrial apoptosis, this study was designed to investigate the role of mitochondrial … Also, esterase activity is very pivotal for the conversion of calcein-AM (no fluorescence) to …

参考文章(35)
Ademola Adetokunbo Oyagbemi, Temidayo Olutayo Omobowale, Akinleye Stephen Akinrinde, Adebowale Bernard Saba, Blessing Seun Ogunpolu, Oluwabusola Daramola, None, Lack of reversal of oxidative damage in renal tissues of lead acetate-treated rats Environmental Toxicology. ,vol. 30, pp. 1235- 1243 ,(2015) , 10.1002/TOX.21994
Emy Basso, Lisa Fante, Jonathan Fowlkes, Valeria Petronilli, Michael A. Forte, Paolo Bernardi, Properties of the Permeability Transition Pore in Mitochondria Devoid of Cyclophilin D Journal of Biological Chemistry. ,vol. 280, pp. 18558- 18561 ,(2005) , 10.1074/JBC.C500089200
Lin Wang, Heng Wang, Maozhi Hu, Jin Cao, Dawei Chen, Zongping Liu, Oxidative stress and apoptotic changes in primary cultures of rat proximal tubular cells exposed to lead. Archives of Toxicology. ,vol. 83, pp. 417- 427 ,(2009) , 10.1007/S00204-009-0425-Z
Jeffrey S. Armstrong, The role of the mitochondrial permeability transition in cell death. Mitochondrion. ,vol. 6, pp. 225- 234 ,(2006) , 10.1016/J.MITO.2006.07.006
Jing Bi, Xiao-bo Wang, Lei Chen, Shuang Hao, Li-jia An, Bo Jiang, Lei Guo, Catalpol protects mesencephalic neurons against MPTP induced neurotoxicity via attenuation of mitochondrial dysfunction and MAO-B activity. Toxicology in Vitro. ,vol. 22, pp. 1883- 1889 ,(2008) , 10.1016/J.TIV.2008.09.007
Emily H-Y Cheng, Tatiana V Sheiko, Jill K Fisher, William J Craigen, Stanley J Korsmeyer, VDAC2 inhibits BAK activation and mitochondrial apoptosis. Science. ,vol. 301, pp. 513- 517 ,(2003) , 10.1126/SCIENCE.1083995
Sanjeev Gupta, George E.N. Kass, Eva Szegezdi, Bertrand Joseph, The mitochondrial death pathway: a promising therapeutic target in diseases. Journal of Cellular and Molecular Medicine. ,vol. 13, pp. 1004- 1033 ,(2009) , 10.1111/J.1582-4934.2009.00697.X
Marieta Barrow Heaton, Kendra Siler-Marsiglio, Michael Paiva, Alexandra Kotler, Jonathan Rogozinski, Stacey Kubovec, Mary Coursen, Vladimir Madorsky, Ethanol influences on Bax associations with mitochondrial membrane proteins in neonatal rat cerebellum. Developmental Neurobiology. ,vol. 73, pp. 127- 141 ,(2013) , 10.1002/DNEU.22042
Arnaud Chevrollier, Dominique Loiseau, Pascal Reynier, Georges Stepien, Adenine nucleotide translocase 2 is a key mitochondrial protein in cancer metabolism Biochimica et Biophysica Acta. ,vol. 1807, pp. 562- 567 ,(2011) , 10.1016/J.BBABIO.2010.10.008
Nurit Keinan, Hadas Pahima, Danya Ben-Hail, Varda Shoshan-Barmatz, The role of calcium in VDAC1 oligomerization and mitochondria-mediated apoptosis. Biochimica et Biophysica Acta. ,vol. 1833, pp. 1745- 1754 ,(2013) , 10.1016/J.BBAMCR.2013.03.017