Cost-effectiveness analysis of negative pressure wound therapy dressings after open inguinal vascular surgery – The randomised INVIPS-Trial

作者: Robert Svensson-Björk , Sanjib Saha , Stefan Acosta , Ulf-G. Gerdtham , Julien Hasselmann

DOI: 10.1016/J.JTV.2020.09.005

关键词: Negative-pressure wound therapyQuadrant (abdomen)MedicinePatient dataIncidence (epidemiology)In patientCost-effectiveness analysisQuality of lifeVascular surgerySurgery

摘要: Abstract Aim While the scientific evidence in favour of negative pressure wound therapy (NPWT) dressings on sutured incisions prevention surgical site infections (SSIs) has increased, cost-effectiveness after vascular surgery not been evaluated. The aim this study was to evaluate NPWT compared standard for SSIs open inguinal surgery. Materials and methods Patient data were retrieved from randomised INVIPS-trial's arm, which included patients either or dressings. surveyed 90 days postoperatively. patients' individual cost analysed a healthcare perspective. quality life measured using Vascuqol-6 questionnaire pre- 30 Cost-effectiveness determined by decreased equal total costs significant reduction SSI incidence. Results : mean procedure-related at €16,621 treated with (n = 59) €16,285 (n = 60), p = 0.85. incidence 11.9% (n = 7/59) 30.0% (n = 18/60) dressings, p = 0.015. This corresponds an increased €1,853 per avoided. plane incremental difference score showed that 42% estimates quadrant where dominant. Conclusion: is considered cost-effective over undergoing due reduced no higher costs.

参考文章(27)
Edward A. McGillicuddy, C. Keith Ozaki, Samir K. Shah, Michael Belkin, Allen Hamdan, Neal Barshes, Mark Wyers, Louis Nguyen, The Impact of Vascular Surgery Wound Complications on Quality of Life Journal of Vascular Surgery. ,vol. 64, pp. 1780- 1788 ,(2015) , 10.1016/J.JVS.2016.05.068
A.P.R. Wilson, M.F. Sturridge, T. Treasure, R.N. Grüneberg, A scoring method (ASEPSIS) for postoperative wound infections for use in clinical trials of antibiotic prophylaxis. The Lancet. ,vol. 327, pp. 311- 312 ,(1986) , 10.1016/S0140-6736(86)90838-X
W. Norman-Taylor, James Scott, John Greenwood, M.E.M. Herford, B. M. A. and the Green-Paper. The Lancet. ,vol. 1, pp. 311- 311 ,(1969) , 10.1016/S0140-6736(69)91070-8
Henry A. Glick, Sample Size and Power for Cost-Effectiveness Analysis (Part 1) PharmacoEconomics. ,vol. 29, pp. 189- 198 ,(2011) , 10.2165/11585070-000000000-00000
Anahita Dua, Sapan S. Desai, Bhavin Patel, Gary R. Seabrook, Kellie R. Brown, Brian Lewis, Peter J. Rossi, Michael Malinowski, Cheong J. Lee, Preventable Complications Driving Rising Costs in Management of Patients with Critical Limb Ischemia. Annals of Vascular Surgery. ,vol. 33, pp. 144- 148 ,(2016) , 10.1016/J.AVSG.2015.11.026
Don Husereau, Michael Drummond, Stavros Petrou, Chris Carswell, David Moher, Dan Greenberg, Federico Augustovski, Andrew H. Briggs, Josephine Mauskopf, Elizabeth Loder, Consolidated Health Economic Evaluation Reporting Standards (CHEERS) Statement PharmacoEconomics. ,vol. 31, pp. 361- 367 ,(2013) , 10.1007/S40273-013-0032-Y
Peter J. Rossi, SreyRam Kuy, Anahita Dua, Sapan Desai, Arshish Dua, Bhavin Patel, Nader Tondravi, Gary R. Seabrook, Kellie R. Brown, Brian D. Lewis, Cheong J. Lee, SreyReath Kuy, Rishi Subbarayan, Surgical Site Infections after Lower Extremity Revascularization Procedures Involving Groin Incisions Annals of Vascular Surgery. ,vol. 28, pp. 53- 58 ,(2014) , 10.1016/J.AVSG.2013.08.002
Melissa M. Boltz, Christopher S. Hollenbeak, Kathleen G. Julian, Gail Ortenzi, Peter W. Dillon, Hospital costs associated with surgical site infections in general and vascular surgery patients Surgery. ,vol. 150, pp. 934- 942 ,(2011) , 10.1016/J.SURG.2011.04.006