ラクターゼ活性を有するタンパク質、該タンパク質をコードする遺伝子、該遺伝子を含有する組み換えベクター、形質転換体、及びその製造方法並びに用途
作者： 公安 礒部 , 芳彦 廣瀬 , 貴史 小山
DOI:
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摘要: ｐＨ１～２においても安定であり、かつ、ｐＨ４～５における活性の高い新規なラクターゼ活性を有するタンパク質を提供すること。 本発明では、ｐＨ３．０～４．０付近で最も活性が高く、安定ｐＨ範囲がｐＨ１．５～７．０であるラクターゼ活性を有するタンパク質を提供する。本発明に係るタンパク質は、空腹時における胃内において安定であり、かつ、食中食後の胃内において、高い活性を示すため、これを有効成分とする酵素製剤、医薬品組成物、医薬部外品組成物又は食品組成物は、食前に摂取することが可能であり、さらに、食中食後においても非常に高い乳糖分解作用を実現することができる。
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