An intronic MYLK variant associated with inflammatory lung disease regulates promoter activity of the smooth muscle myosin light chain kinase isoform.
作者： Yoo Jeong Han , Shwu-Fan Ma , Michael S. Wade , Carlos Flores , Joe G. N. Garcia
DOI: 10.1007/S00109-011-0820-9
关键词: Enhancer 、 Transcription factor 、 Gene isoform 、 Molecular biology 、 Myosin light-chain kinase 、 MYLK 、 Myosin 、 Lung injury 、 Biology 、 Repressor
摘要: … regulation in inflammatory lung diseases such as ALI and asthma, FOXN1-governed transcriptional regulation may play a critical role in the development of inflammatory lung diseases. …
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