Injectable polymeric carriers for gene delivery systems

摘要: Abstract: Cationic polymers that have shown significant promise as gene delivery agents are more effective than the state-of-the art, commercially available non-viral systems. Gene in vivo involves interactions with biophase (the effect site of drug) prior to reaching target cells which complicates efforts understand mechanism process. The ability incorporate genetic materials such DNA, RNA and siRNAs into functionalized nanoparticles demonstrates a new era. In this chapter, we highlight basic overview injectable polymeric carriers been reported safe successful vectors, their formulations success thereof. addition, outline various strategies for designing overcome biological barriers vectors.