Mutant p53 in breast cancer: potential as a therapeutic target and biomarker.

作者: Michael J. Duffy , Naoise C. Synnott , John Crown

DOI: 10.1007/S10549-018-4753-7

关键词: Biomarker (medicine)High prevalencePotential biomarkersCancer researchGeneBreast cancerRetrospective cohort studyMutantMedicineDisease

摘要: … breast cancer, especially the TN subtype. The aims of this article are therefore to discuss the role of mutant p53 in breast cancer… As the structure of p53 and its role in suppressing cancer …

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