Neuropsychiatric symptoms associated with efavirenz: prevalence, correlates, and management. A neurobehavioral review.
作者： Bonaventura Clotet , José A Muñoz-Moreno , Carmina R Fumaz , Eugènia Negredo , Marian González-García
DOI:
关键词: MEDLINE 、 Psychological intervention 、 Antiretroviral therapy 、 Reverse-transcriptase inhibitor 、 Adverse effect 、 Medicine 、 In patient 、 Pediatrics 、 Efavirenz 、 Psychiatry
摘要: The non-nucleoside analog reverse transcriptase inhibitor efavirenz is one of the most common components HAART. Neuropsychiatric symptoms are frequently reported in patients taking efavirenz-based regimens. These usually transient, although they can sometimes persist for up to two years after initiation treatment. This review describes detail neuropsychiatric related efavirenz, outlines relevant and recent findings on this agent, suggests possible interventions based neurobehavioral results. Different recommendations assessment efavirenz-related adverse events also provided.
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