Successful Treatment of Cerebral Mucormycosis with Amphotericin B

作者: Gerard N. Burrow

DOI: 10.1001/JAMA.1963.63700050034023A

关键词: Amphotericin BDIABETIC ACIDOSISDiseaseMucormycosisMedicineDiabetes mellitusAntibioticsPediatricsNoseSurgeryIn patient

摘要: RECENT REPORTS of recovery from mucormycosis following the appropriate therapy 1,2 have stimulated renewed interest in disease. Mucormycosis is caused by tissue invasion saprophytic fungi genus Mucor . The disease occurs patients who debilitating diseases, or received antibiotics, steroids, anti-tumor agents, and particularly prone to develop with diabetic acidosis. Forty-two percent cases a recent review 3 were diabetic. Cerebral mucormycosis, most common form disease, associated an extremely high mortality. Only six survivals 1,4-7 been reported, all those described left residual deficits (see table). present case because diagnosis was made early on basis certain previously criteria 8,9 begun amphotericin B. Despite disturbing side effects drug, continued, patient

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