Validity and reliability of a rating scale on subjective cognitive deficits in bipolar disorder (COBRA).

摘要: Abstract Background Discrepancies between bipolar patients' reports and neuropsychological testing have been described replicated. Unfortunately, no valid, specific, user-friendly, brief instrument is available to measure cognitive deficits as reported by these patients. The main aim of this study was validate a novel named the “cognitive complaints in disorder rating assessment” (COBRA). Second, we investigated relationship COBRA, objective measures illness course variables. Method total sample (N=215) included 91 patients 124 healthy controls. psychometric properties COBRA (e.g. internal consistency, concurrent validity, discriminative factorial analyses, ROC curve feasibility) were analyzed. A complete battery used assessment. Results had one-factor structure with very high consistency (Cronbach's alpha=0.913). convergent validity indicated strong correlation Frankfurt Complaint Questionnaire (ro=0.888, p Limitations cross-sectional design study, influence medication severity included. Conclusions showed be useful assess overall satisfactory properties. Cognitive partially correlated memory executive function issues that may increase subjective perception deficits, such subthreshold depressive symptoms number episodes.