Dynamics of Fst for the island model.

作者: Sivan Rottenstreich , Matthew B. Hamilton , Judith R. Miller

DOI: 10.1016/J.TPB.2007.08.007

关键词: Coalescent theoryDemeGenetic driftPopulationEcologyApplied mathematicsBiologyState (functional analysis)Measure (mathematics)Effective population sizeRandom variable

摘要: Abstract F st is a measure of genetic differentiation in subdivided population. Sewall Wright observed that = 1 + 2 Nm haploid diallelic infinite island model, where N the effective population size each deme and m migration rate. In demonstrating this result, relied on Natural populations are not therefore they change over time due to drift. finite population, becomes random variable evolves time. work we ask, given an initial state, what dynamics mean variance under model? application both these quantities critical evaluation data. We show after order generations slightly biased below . Further d number demes introduce several new mathematical techniques analyze coalescent genealogies dynamic setting.

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