9 – Calcitonin Treatment in Postmenopausal Osteoporosis

作者: Stuart L. Silverman

DOI: 10.1016/B978-012068705-3/50010-3

关键词: PlaceboPregnancyNasal sprayCalciumCalcitoninHomeostasisEndocrinologyAnalgesicInternal medicineOsteoporosisMedicine

摘要: Calcitonin is a safe treatment for established osteoporosis and currently available as an injectable preparation. Clinical trials with either or nasal spray forms of salmon calcitonin have demonstrated the efficacy in increasing lumbar spine bone mass decreasing vertebral fracture rates (nasal form) patients osteoporosis. The use has been limited by decreased compliance due to side effects method delivery. availability formulation relatively few compared placebo increased convenience use. Both demonstrate analgesic osteoporotic individuals. also prevents hypercalcemia following calcium rich meals protects stores during periods stress such pregnancy, lactation, low dietary intake. Despite these biological responses, does not significant role homeostasis plasma normal

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