Patterns of cell death induced by metformin in human MCF-7 breast cancer cells.

作者: Natália Medeiros Dias Lopes , Poliana Camila Marinello , Larissa Juliani Sanches , Walison Augusto da Silva Brito , Maria Isabel Lovo-Martins

DOI: 10.1016/J.PRP.2020.153199

关键词: Programmed cell deathMetforminApoptosisMedicineCancer researchRIPK1Oxidative stressNecroptosisMCF-7Tumor progression

摘要: … importance of necroptosis, ferroptosis and apoptosis in the toxicity of metformin to MCF-7 … alter other cellular processes, like the upregulation of hypoxia-inducible factor-1alpha (HIF-1α) […

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