Surgery for pharmacoresistant epilepsy in the developing world: A pilot study

作者: Warren Boling , Adriana Palade , Angela Wabulya , Nicoletta Longoni , Benjamin Warf

DOI: 10.1111/J.1528-1167.2008.01984.X

关键词: Developed countryYoung adultEpilepsy surgeryTemporal lobeSurgeryPharmacotherapyNeuropsychologyDeveloping countryMedicineEpilepsy

摘要: Epilepsy prevalence in the developing world is many fold that found developed countries. For individuals whose conditions failed to respond pharmacotherapy, surgery only opportunity for cure. In Uganda, we a center treatment of intractable temporal lobe epilepsy (iTLE) functions within technologic and expertise constraints severely low resource area. Our model relies on partnership with professionals training local staff. Patients were prescreened at regional clinics iTLE. Individuals meeting inclusion criteria referred treating Ugandan hospital (CURE Children's' Hospital CCHU) video-EEG (electroencephalography), computed tomography (CT) imaging, neuropsychological evaluation. Data transferred experts analysis recommendations. Ten patients diagnosed iTLE surgically treated CCHU. Six (60%) seizure free, there was no neurologic morbidity or mortality. surgical pharmacoresistant TLE has functioned successfully true setting.

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