Survival and Growth of Prostate Cancer Cells in the Bone: Role of the Alpha-Receptor for Platelet-Derived Growth Factor in Supporting Early Metastatic Foci

作者: Qingxin Liu , Yun Zhang , Danielle Jernigan , Alessandro Fatatis

DOI: 10.1007/978-94-007-2558-4_11

关键词: ComplicationZoledronic acidStandard of careProstate cancerSecondary tumorsInternal medicineAdrenergic receptorDiseaseOncologyMedicinePlatelet-derived growth factor

摘要: Skeletal dissemination is by far the most feared complication of prostate cancer and main cause patients’ demise. Today, 85% patients are diagnosed with in absence clinically evident secondary tumors. However, a significant number these will eventually develop advanced form disease present skeletal metastases. A definitive, curative treatment for bone metastatic still an unmet clinical need current standard care relies on merely palliative measures.

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