Articular cartilage calcification of the hip and knee is highly prevalent, independent of age but associated with histological osteoarthritis: evidence for a systemic disorder

摘要: Summary Objectives Based on the concept of a systemic predisposition for articular cartilage calcification (CC), aim this study was to determine prevalence and amount bilateral CC hip knee joints in an unselected sample cohort by high-resolution digital contact radiography (DCR) analyze association with histological OA. Methods Both 87 donors (48 m 39 f; mean age 62) were analyzed DCR post-mortem donors. Histological OA (OARSI) main load bearing area femoral heads medial condyles determined. Results The head 96.6%, 94.3%. Bilateral detected 79.3% hips 86.2% knees. Concomitant all four 69.0% There no difference between knees ( P  = 0.47). any given or correlated that contralateral r s  = 0.54,  = 0.50,  = 0.48,  = 0.30,  = 0.004), but not (hips  = −0.09,  = 0.42;  = 0.10,  = 0.34). Conclusions These data support occurs as result disorder. appears be early element pathogenesis independent age.