Evidence for GTP-binding protein involvement in the tyrosine phosphorylation of the T cell receptor zeta chain.
作者： C Cenciarelli , R.J. Hohman , T.P. Atkinson , F Gusovsky , A.M. Weissman
DOI: 10.1016/S0021-9258(18)42068-6
关键词: Cell surface receptor 、 Biochemistry 、 Protein tyrosine phosphatase 、 Guanosine 、 Phosphorylation 、 GTP' 、 Biology 、 Tyrosine phosphorylation 、 Molecular biology 、 Receptor tyrosine kinase 、 Tyrosine kinase
摘要: The zeta subunit of the T cell receptor (TCR) is a prominent substrate for TCR-activated tyrosine kinase. Tyrosine phosphorylation in response to antibody-mediated cross-linking was synergized permeabilized cells by either two non-hydrolyzable GTP analogues, guanosine 5'-[gamma-thio]triphosphate (GTP gamma S) or 5'-[beta, gamma-imido]triphosphate Gpp(NH)p. ATP analogues did not significantly affect antibody-induced phosphorylation. Unlike GDP analogue 5'-[beta-thio]diphosphate (GDP beta enhance zeta. effect induced required TCR occupancy and independent protein kinase C. Taken together these observations implicate GTP-binding modulation TCR-induced
sci-hub.st 参考文章(40)
M.E. Peter, C. Hall, A. Rühlmann, J. Sancho, C. Terhorst, The T-cell receptor zeta chain contains a GTP/GDP binding site. The EMBO Journal. ,vol. 11, pp. 933- 941 ,(1992) , 10.1002/J.1460-2075.1992.TB05132.X
M.D. Patel, L.E. Samelson, R.D. Klausner, Multiple kinases and signal transduction. Phosphorylation of the T cell antigen receptor complex. Journal of Biological Chemistry. ,vol. 262, pp. 5831- 5838 ,(1987) , 10.1016/S0021-9258(18)45650-5
M Baniyash, P Garcia-Morales, E Luong, L E Samelson, R D Klausner, The T cell antigen receptor zeta chain is tyrosine phosphorylated upon activation. Journal of Biological Chemistry. ,vol. 263, pp. 18225- 18230 ,(1988) , 10.1016/S0021-9258(19)81349-2
J.P. Secrist, L. Karnitz, R.T. Abraham, T-cell antigen receptor ligation induces tyrosine phosphorylation of phospholipase C-gamma 1. Journal of Biological Chemistry. ,vol. 266, pp. 12135- 12139 ,(1991) , 10.1016/S0021-9258(18)98869-1
D G Orloff, S J Frank, F A Robey, A M Weissman, R D Klausner, Biochemical characterization of the eta chain of the T-cell receptor. A unique subunit related to zeta. Journal of Biological Chemistry. ,vol. 264, pp. 14812- 14817 ,(1989) , 10.1016/S0021-9258(18)63772-X
J D Graves, D A Cantrell, An analysis of the role of guanine nucleotide binding proteins in antigen receptor/CD3 antigen coupling to phospholipase C. Journal of Immunology. ,vol. 146, pp. 2102- 2107 ,(1991)
E Bonvini, K E Debell, M S Taplits, C Brando, A Laurenza, K Seamon, T Hoffman, A role for guanine-nucleotide-binding proteins in mediating T-cell-receptor coupling to inositol phospholipid hydrolysis in a murine T-helper (type II) lymphocyte clone. Biochemical Journal. ,vol. 275, pp. 689- 696 ,(1991) , 10.1042/BJ2750689
J Y Wang, Isolation of antibodies for phosphotyrosine by immunization with a v-abl oncogene-encoded protein. Molecular and Cellular Biology. ,vol. 5, pp. 3640- 3643 ,(1985) , 10.1128/MCB.5.12.3640
H Schrezenmeier, G Ahnert-Hilger, B Fleischer, A T cell receptor-associated GTP-binding protein triggers T cell receptor-mediated granule exocytosis in cytotoxic T lymphocytes. Journal of Immunology. ,vol. 141, pp. 3785- 3790 ,(1988)
A. Weiss, G. Koretzky, R. C. Schatzman, T. Kadlecek, Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 88, pp. 5484- 5488 ,(1991) , 10.1073/PNAS.88.13.5484