The Fate of Acute Methicillin-Resistant Staphylococcus aureus Periprosthetic Knee Infections Treated by Open Debridement and Retention of Components
作者： Thomas Bradbury , Thomas K. Fehring , Michael Taunton , Arlen Hanssen , Khalid Azzam
DOI: 10.1016/J.ARTH.2009.04.028
关键词: Antibiotics 、 Retrospective cohort study 、 Methicillin-resistant Staphylococcus aureus 、 Staphylococcus aureus 、 Debridement 、 Arthroplasty 、 Surgery 、 Periprosthetic 、 Medicine 、 Knee Joint
摘要: The success of open irrigation and debridement with component retention (ODCR) for acute periprosthetic knee joint infection varies widely. species virulence the infecting organism have been shown to influence outcome. This multicenter, retrospective study identified 19 cases methicillin-resistant Staphylococcus aureus (MRSA) infections managed by ODCR at least 4 weeks postoperative intravenous vancomycin therapy. At minimum follow-up 2 years, treatment failed eradicate in 16 (84% failure rate). Of those failures, 13 patients required a 2-stage exchange arthroplasty, repeat incision antibiotic suppression, 1 patient died MRSA sepsis. In addition, systematic review literature revealed 10 similar protocol. total rate was 18%.
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