Screening for Kinase Inhibitors: From Biochemical to Cellular Assays

Müller R, Bravo R, Curran T, Transient induction of c-fos and c-myc in an immediate consequence of growth factor stimulation. Cancer surveys. ,vol. 4, pp. 655- ,(1985)

D L Marquardt, J L Alongi, L L Walker, The phosphatidylinositol 3-kinase inhibitor wortmannin blocks mast cell exocytosis but not IL-6 production. Journal of Immunology. ,vol. 156, pp. 1942- 1945 ,(1996)

Antonio Jimeno, Belen Rubio-Viqueira, Maria L. Amador, Darin Oppenheimer, Nadia Bouraoud, Peter Kulesza, Valeria Sebastiani, Anirban Maitra, Manuel Hidalgo, Epidermal Growth Factor Receptor Dynamics Influences Response to Epidermal Growth Factor Receptor Targeted Agents Cancer Research. ,vol. 65, pp. 3003- 3010 ,(2005) , 10.1158/0008-5472.CAN-04-3586

Paolo Vigneri, Jean Y. J. Wang, Induction of apoptosis in chronic myelogenous leukemia cells through nuclear entrapment of BCR–ABL tyrosine kinase Nature Medicine. ,vol. 7, pp. 228- 234 ,(2001) , 10.1038/84683

Martin Offterdinger, Virginie Georget, Andreas Girod, Philippe I. H. Bastiaens, Imaging Phosphorylation Dynamics of the Epidermal Growth Factor Receptor Journal of Biological Chemistry. ,vol. 279, pp. 36972- 36981 ,(2004) , 10.1074/JBC.M405830200

Carolyn M. Discafani, Marion L. Carroll, M.Brawner Floyd, Irwin J. Hollander, Zaheed Husain, Bernard D. Johnson, Douglas Kitchen, Michael K. May, Madhu S. Malo, Albert A. Minnick, Ramaswamy Nilakantan, Ru Shen, Yu-Fen Wang, Allan Wissner, Lee M. Greenberger, Irreversible inhibition of epidermal growth factor receptor tyrosine kinase with In Vivo activity by N-[4-[(3-bromophenyl)amino]-6-quinazolinyl]-2-butynamide (CL-387,785) Biochemical Pharmacology. ,vol. 57, pp. 917- 925 ,(1999) , 10.1016/S0006-2952(98)00356-6

Ellen Weisberg, Christina Boulton, Louise M Kelly, Paul Manley, Doriano Fabbro, Thomas Meyer, D.Gary Gilliland, James D Griffin, Inhibition of mutant FLT3 receptors in leukemia cells by the small molecule tyrosine kinase inhibitor PKC412. Cancer Cell. ,vol. 1, pp. 433- 443 ,(2002) , 10.1016/S1535-6108(02)00069-7

J. S. Melnick, J. Janes, S. Kim, J. Y. Chang, D. G. Sipes, D. Gunderson, L. Jarnes, J. T. Matzen, M. E. Garcia, T. L. Hood, R. Beigi, G. Xia, R. A. Harig, H. Asatryan, S. F. Yan, Y. Zhou, X.-J. Gu, A. Saadat, V. Zhou, F. J. King, C. M. Shaw, A. I. Su, R. Downs, N. S. Gray, P. G. Schultz, M. Warmuth, J. S. Caldwell, An efficient rapid system for profiling the cellular activities of molecular libraries. Proceedings of the National Academy of Sciences of the United States of America. ,vol. 103, pp. 3153- 3158 ,(2006) , 10.1073/PNAS.0511292103

Huaxian Chen, Joy Kovar, Sean Sissons, Karen Cox, William Matter, Fred Chadwell, Peng Luan, Chris J. Vlahos, Amy Schutz-Geschwender, D. Michael Olive, A cell-based immunocytochemical assay for monitoring kinase signaling pathways and drug efficacy. Analytical Biochemistry. ,vol. 338, pp. 136- 142 ,(2005) , 10.1016/J.AB.2004.11.015

Ivan C. King, Ming Feng, Joseph J. Catino, High throughput assay for inhibitors of the epidermal growth factor receptor-associated tyrosine kinase Life Sciences. ,vol. 53, pp. 1465- 1472 ,(1993) , 10.1016/0024-3205(93)90619-E