Transitioning to highly effective therapies for the treatment of chronic hepatitis C virus infection: a policy statement and implementation guideline.

作者: Daniel J Smyth , Duncan Webster , Lisa Barrett , Mark MacMillan , Lisa McKnight

DOI: 10.1155/2014/109046

关键词: Mass screeningIntensive care medicineHealth careGuidelineMedicineHealth policyCohort studyLiver transplantationPhysical therapyHepatocellular carcinomaIndirect costs

摘要: Chronic hepatitis C virus (HCV) infection increases all-cause mortality, rates of cirrhosis, hepatocellular carcinoma, liver transplantation and overall health care utilization. Morbidity mortality disproportionately affect individuals born between 1945 1975. The recent development well-tolerated highly effective therapies for chronic HCV represents a unique opportunity to dramatically reduce HCV-related complications their costs. Critical the introduction such will be well-designed provincial programming ensure immediate treatment access at highest risk complication, well-defined strategies address global needs traditionally high-risk marginalized populations. practitioners in New Brunswick created strategy that stratifies according those need, measures clinical impact, creates evaluation demonstrate significant direct indirect cost savings anticipated with curative treatments.

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