Pharmacological characterization of FE 201874, the first selective high affinity rat V1A vasopressin receptor agonist.
作者： Rafik Marir , Anne Virsolvy , Kazimierz Wisniewski , Julie Mion , Dominique Haddou
DOI: 10.1111/BPH.12249
关键词: Agonist 、 Partial agonist 、 Vasopressin receptor 、 HEK 293 cells 、 Receptor 、 Inverse agonist 、 Arginine vasopressin receptor 1B 、 Biology 、 Pharmacology 、 Arginine vasopressin receptor 2 、 Biochemistry
摘要: BACKGROUND AND PURPOSE Distinct vasopressin receptors are involved in different physiological and behavioural functions. Presently, no selective agonist is available to specifically elucidate the functional roles of V1A receptor rat, one most widely used animal models. FE 201874 a new derivative human F180. In this study, we performed multi-approach pharmacological characterization determine whether it for receptors.
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